1.the acute treatment time of ischemic cerebrovascular disease is very important. time is the brain. if the patient is within the 4.5hours time window of onset, the blood vessels can be fused by RTPA thrombolysis to restore some neurological functions of the patient misses the time window, such as the time of large vessel occlusion for more than eight hours, the patient ca only do basic thrombolysis, not thrombectomy or antiplatelet therapy 

2.pneumonic changes, aphasia, neglect, homonymous hemianopsia

if the whole entire middle cerebral artery is blocked, then the result is a large vessel stroke that affects the whole entire middle cerebral artery territory which is very region of the brain that receives blood through the middle cerebral artery