1.Cerebrovascular disease includes a variety of medical conditions that affect the blood vessels of the brain and the cerebral circulation. Arteries supplying oxygen and nutrients to the brain are often damaged or deformed in these disorders. The most common presentation of cerebrovascular disease is an ischemic stroke or mini-stroke and sometimes a hemorrhagic stroke. Hypertension is the most important contributing risk factor for stroke and cerebrovascular diseases as it can change the structure of blood vessels and result in atherosclerosis. Atherosclerosis narrows blood vessels in the brain, resulting in decreased cerebral perfusion. Other risk factors that contribute to stroke include smoking and diabetes. Narrowed cerebral arteries can lead to ischemic stroke, but continually elevated blood pressure can also cause tearing of vessels, leading to a hemorrhagic stroke

2.Symptoms of MCA stroke are consistent with the symptoms people usually associate with strokes, such as weakness and/or numbness on one side, facial droop, and difficulties with speakingIf the middle cerebral artery itself is blocked, then the result is a large-vessel stroke that affects the entire middle cerebral artery territory, which is every region of the brain that receives blood through the middle cerebral artery.